There is a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to lower afferent soreness transmission and make analgesia. Therefore, medicines like clonidine that concentrate on alpha-two receptors can affect the transmission of discomfort. Relates to clonidine: oral tablet, oral https://bjorkx950riz6.oneworldwiki.com/user