The netlist generated from the schematic seize will be the input with the structure design from the printed circuit board. The PCB substrate product and stack-up are decided In this particular stage. The layout design with part placement and routing is concluded as per the DFM (Design for manufacturability) suggestions. https://eduardoherhv.tribunablog.com/helping-the-others-realize-the-advantages-of-electronic-design-service-42389109